Dr. Chung’s clinical activities focus on diseases of the liver (primarily cancer and liver transplantation), the biliary tree and the pancreas. His research has been focused upon the modulation of the immune system in animal and human studies as it relates to transplantation and cancer. More specifically, the development of new strategies for monitoring the immune status of transplant recipients and evaluation of novel tolerance inducing regimens in animal models of transplantation. His research group has devised methods for specifically examining the alloreactive T cell subpopulation in transplant recipients’ peripheral blood cells showing that the cytokine production profile of these cells can be correlated at the population level with graft clinical status. Dr. Chung is currently part of a transplant immunology research team examining the gene expression profile of immune cells from transplant recipients in order to develop methods of immunomonitoring to predict transplant graft rejection or accommodation. These principles of immunological evaluation have also been applied to assessment of predicting outcomes of patients undergoing surgical resections for liver and pancreatic cancer.
Dr. Chung also has educational interests in surgical sciences, especially related to liver diseases and transplantation immunology. He is involved in undergraduate, postgraduate and continuing medical education in these areas, has established a university-wide symposium for faculty and students in transplantation, and has organized several postgraduate surgical and research educational forums. Dr. Chung also heads the CIHR/MSFHR Strategic Health Training Program in Transplantation. This program involving many investigators and clinicians is also supported by the VGH & UBC Hospital Foundation, the Vancouver Coastal Health Research Institute, and Fujisawa Canada.